Exercise & Endurance - page 3 Scientific Publications

Latest publication 04/01/2018

Assessment of the effects of exercise on a murine model of OA

International guidelines recommend exercise to delay rapid progression of osteoarthritis (OA). Numerous studies have shown that land-based exercise...

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    [title] => Assessment of the effects of exercise on a murine model of OA
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Authors
C. Huesa, L. Dunning, K. MacDougall, A. Ortiz, M. Villaluz, M. Fegen, A. Crilly, G. Litherland, R. van t Hof, C. Goodyear, J.C. Lockhart

 Lab
Univ. of the West of Scotland, Glasgow, United Kingdom
Journal
Osteoarthritis and Cartilage
Abstract
International guidelines recommend exercise to delay rapid progression of osteoarthritis (OA). Numerous studies have shown that land-based exercise regimes, when performed regularly, leads to an improvement in joint mobility and pain. In vivo models of OA mimic many of the parameters of post-traumatic human OA. Destabilization of the medial meniscus (DMM) in rodents results in progressive development of OA with cartilage damage, osteosclerosis, mild synovitis, ligament damage/calcification and osteophyte formation.
BIOSEB Instruments Used
Activmeter (BIO-ACTIV-R)
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The uncomplicated way to monitor rodent activity over several days from their home cage without manual effort. Based only on weight analysis, Bioseb's ACTIVMETER is an innovative actimeter that measures accurately Activity and Locomotion of rodents (mice and rats) whatever the lights conditions.
fiber_new Now with the possibility to add the measurement of animals’ vertical activity in the home cage (optional).

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