Publications

Latest publication 08/19/2015

Assessment of muscle mass and strength in mice

Muscle weakness is an important phenotype of many diseases that is linked to impaired locomotion and increased mortality. The force that a muscle...

Array
(
    [id_prestablog_news] => 744
    [id_shop] => 1
    [date] => 2015-08-19 00:00:00
    [date_modification] => 2024-02-09 14:15:12
    [langues] => ["1","2"]
    [actif] => 1
    [slide] => 0
    [url_redirect] => 
    [average_rating] => 
    [number_rating] => 
    [author_id] => 1
    [featured] => 0
    [prim_key] => 1453
    [id_lang] => 1
    [title] => Assessment of muscle mass and strength in mice
    [paragraph] => Assessment of muscle mass and strength in mice
    [content] => 
Authors
Andrea Bonetto,	Daniel C Andersson	& David L Waning

 Lab
Department of Surgery, Indiana University School of Medicine, Indianapolis, IN, USA
Journal
BoneKEy Reports
Abstract
Muscle weakness is an important phenotype of many diseases that is linked to impaired locomotion and increased mortality. The force that a muscle can generate is determined predominantly by muscle size, fiber type and the excitation–contraction coupling process. Here we describe methods for the histological assessment of whole muscle to determine fiber cross-sectional area and fiber type, determination of changes in myocyte size using C2C12 cells, in vivo functional tests and measurement of contractility in dissected whole muscles. The extensor digitorum longus and soleus muscles are ideally suited for whole-muscle contractility, and dissection of these muscles is described.
BIOSEB Instruments Used
Grip strength test (BIO-GS3)
    [meta_description] => 
    [meta_keywords] => http://www.nature.com/bonekeyreports/2015/150819/bonekey2015101/full/bonekey2015101.html
    [meta_title] => 
    [link_rewrite] => assessment-of-muscle-mass-and-strength-in-mice
    [actif_langue] => 1
    [read] => 1157
    [count_comments] => 0
    [id] => 744
    [categories] => Array
        (
            [63] => Array
                (
                    [id_prestablog_categorie] => 63
                    [title] => General muscular system
                    [link_rewrite] => General-muscular-system
                )

            [20] => Array
                (
                    [id_prestablog_categorie] => 20
                    [title] => Muscular system
                    [link_rewrite] => Muscular-system
                )

            [2] => Array
                (
                    [id_prestablog_categorie] => 2
                    [title] => Publications
                    [link_rewrite] => publications
                )

        )

    [authors] => 
    [paragraph_crop] => Assessment of muscle mass and strength in mice
    [link_for_unique] => 1
    [products_liaison] => Array
        (
            [48] => Array
                (
                    [name] => Grip strength test
                    [description_short] => 
An easy way to objectively quantify the muscular strength of mice and rats, and to assess the effect of drugs, toxins, muscular (i.e. myopathy) and neurodegenerative diseases on muscular degeneration. It is widely used in conjunction with the ROTAROD motor coordination test: a normally coordinated rodent will show a decreased latency to fall off the rotating rod if its muscular strength is low. The Grip Strength Test is a must for your research on activity, motor control & coordination, and is particularly well suited for studies on Parkinson's & Huntington's disease.
New features GS4 - 2023: Color display with permanent backlight screen for easier reading, reset by footswitch, Improved battery time, Larger data memory of 500 values, Animal counter, USB port (charging/data transfer)

                    [thumb] => 
                    [img_empty] => /var/www/vhosts/de3310.ispfr.net/preprod.bioseb.com/modules/prestablog/views/img/product_link_white.jpg
                    [image_presente] => 1
                    [link] => https://preprod.bioseb.com/en/activity-motor-control-coordination/48-grip-strength-test.html
                )

        )

)
1