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Dernière publication 23/07/2022

Neuromuscular mechanisms of weakness in a mouse model of chronic alcoholic myopa

Weakness is a common clinical symptom reported in individuals with chronic alcohol use disorder. However, it remains unclear whether low strength...

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    [title] => Neuromuscular mechanisms of weakness in a mouse model of chronic alcoholic myopa
    [paragraph] => Neuromuscular mechanisms of weakness in a mouse model of chronic alcoholic myopathy
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Authors
SE Moser, AM Brown, BC Clark



 Lab
Department of Biomedical Sciences, Ohio University, Athens, Ohio, USA


Journal
Alcoholism: Clinical and Experimental Research


Abstract
Weakness is a common clinical symptom reported in individuals with chronic alcohol use disorder. However, it remains unclear whether low strength in these individuals is directly related to excessive ethanol intake, other deleterious factors (lifestyle, environment, genetics, etc.), or a combination of both. Therefore, we examined whether (and how) ethanol reduces the muscle’s force-producing capacity using a controlled in vivo preclinical mouse model of excessive ethanol intake.
BIOSEB Instruments Used
Grip strength test (BIO-GS3)

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Une méthode simple pour quantifier objectivement la force musculaire des rats et souris et l'effet de drogues, toxines, maladies musculaires (ex: myopathie) et neurodégénératives. Cette mesure de force est souvent employée en association avec le test de coordination motrice ROTAROD: un sujet présentant une coordination normale montrera des résultats médiocres en cas de faible force musculaire. Un must pour vos recherches sur l'activité, la coordination et le contrôle musculaire: particulièrement utile pour vos études sur les maladies de Parkinson et Huntington.


Nouveautés GS4 - 2023: Écran couleur rétroéclairé (meilleure lisibilité), pédale de remise à zéro, durée de batterie optimisée, taille de mémoire augmentée à 500 valeurs, compteur d'animaux, port USB (transfert de données/charge)


Instrument for ratsInstrument for mice

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