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Peripheral sensitization and neuropathic pain in the rat medial meniscal tear mo

Post-traumatic osteoarthritis (PTOA) accounts for 12% of all osteoarthritis cases. Lesions of the medial meniscus are a risk factor for the...

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    [title] => Peripheral sensitization and neuropathic pain in the rat medial meniscal tear mo
    [paragraph] => Peripheral sensitization and neuropathic pain in the rat medial meniscal tear model of post-traumatic osteoarthritis
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Authors



 Lab
Dalhousie University, Halifax, NS, Canada


Journal
Osteoarthritis and Cartilage


Abstract
Post-traumatic osteoarthritis (PTOA) accounts for 12% of all osteoarthritis cases. Lesions of the medial meniscus are a risk factor for the development of PTOA and also increase the susceptibility to neuropathic pain. While PTOA pain can stem from instability-induced joint degeneration, we hypothesise that a proportion of the pain is due to nerve damage. This study aimed to characterise PTOA pain from multiple angles in the medial meniscus transection (MMT) model of joint instability.

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