Publications

Dernière publication 01/02/2019

Protective effects of Liuwei dihuang water extracts on diabetic muscle atrophy

In C2C12 myotubes, LWDH-WE attenuated MG-induced cellular death and oxidative damage accompanied with improving mitochondrial membrane potential,...

Array
(
    [id_prestablog_news] => 1081
    [id_shop] => 1
    [date] => 2019-02-01 00:00:00
    [date_modification] => 2024-02-09 14:15:12
    [langues] => ["1","2"]
    [actif] => 1
    [slide] => 0
    [url_redirect] => 
    [average_rating] => 
    [number_rating] => 
    [author_id] => 1
    [featured] => 0
    [prim_key] => 2124
    [id_lang] => 2
    [title] => Protective effects of Liuwei dihuang water extracts on diabetic muscle atrophy
    [paragraph] => Protective effects of Liuwei dihuang water extracts on diabetic muscle atrophy
    [content] => 
Authors
YT Tseng, WH Chang, CC Lin, FR Chang, PC Wu

 Lab
College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan
Journal
Phytomedicine
Abstract
In C2C12 myotubes, LWDH-WE attenuated MG-induced cellular death and oxidative damage accompanied with improving mitochondrial membrane potential, inhibiting NADPH oxidase (Nox) activation, and ROS production. Moreover, LWDH-WE could attenuate MG-induced atrophy of C2C12 myotubes accompanied with regulating protein synthesis (IGF-1R, Akt, mTOR) and protein degradation (FoxO3a, atrogin-1, MuRF-1) signals. In STZ-induced diabetic mice, LWDH-WE improved body weight and skeletal muscle mass of mice. LWDH-WE also enhanced muscle strength of STZ-induced diabetic mice. Furthermore, LWDH-WE enhanced the improvement of insulin on gastrocnemius muscle mass and grip strength in STZ-treated mice.
BIOSEB Instruments Used
Grip strength test (BIO-GS3)
    [meta_description] => 
    [meta_keywords] => https://www.sciencedirect.com/science/article/pii/S0944711318303131
    [meta_title] => 
    [link_rewrite] => protective-effects-of-liuwei-dihuang-water-extracts-on-diabetic-muscle-atrophy
    [actif_langue] => 1
    [read] => 960
    [count_comments] => 0
    [id] => 1081
    [categories] => Array
        (
            [81] => Array
                (
                    [id_prestablog_categorie] => 81
                    [title] => Diabète, Insuline & Glucose
                    [link_rewrite] => Diabète-Insuline-Glucose
                )

            [23] => Array
                (
                    [id_prestablog_categorie] => 23
                    [title] => Métabolisme
                    [link_rewrite] => Metabolisme
                )

            [2] => Array
                (
                    [id_prestablog_categorie] => 2
                    [title] => Publications
                    [link_rewrite] => publications
                )

        )

    [authors] => 
    [paragraph_crop] => Protective effects of Liuwei dihuang water extracts on diabetic muscle atrophy
    [link_for_unique] => 1
    [products_liaison] => Array
        (
            [48] => Array
                (
                    [name] => Test d'agrippement
                    [description_short] => 
Une méthode simple pour quantifier objectivement la force musculaire des rats et souris et l'effet de drogues, toxines, maladies musculaires (ex: myopathie) et neurodégénératives. Cette mesure de force est souvent employée en association avec le test de coordination motrice ROTAROD: un sujet présentant une coordination normale montrera des résultats médiocres en cas de faible force musculaire. Un must pour vos recherches sur l'activité, la coordination et le contrôle musculaire: particulièrement utile pour vos études sur les maladies de Parkinson et Huntington.
Nouveautés GS4 - 2023: Écran couleur rétroéclairé (meilleure lisibilité), pédale de remise à zéro, durée de batterie optimisée, taille de mémoire augmentée à 500 valeurs, compteur d'animaux, port USB (transfert de données/charge)

                    [thumb] => 
                    [img_empty] => /var/www/vhosts/de3310.ispfr.net/preprod.bioseb.com/modules/prestablog/views/img/product_link_white.jpg
                    [image_presente] => 1
                    [link] => https://preprod.bioseb.com/fr/activite-systeme-moteur-coordination/48-grip-strength-test.html
                )

        )

)
1